The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Avulsion or shearing ... • Non-union of fracture ... #msk #diagnosis ... #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... post-inflammatory healing ... post-inflammatory tissue healing ... FrozenShoulder #pathophysiology ... #staging #msk
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... Inflammatory Stage ... #Fracture #Healing ... #msk #Staging # ... pathophysiology
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Secrecy surrounding eating ... inducing vomiting #BulimiaNervosa ... #pathophysiology ... signs #symptoms #psychiatry
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Lots of fluid, takes ... forces that are wearing ... Larger, weight-bearing ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
hunger and satiety states ... physiological/emotional states ... over mistakes #BulimiaNervosa ... #pathophysiology ... signs #symptoms #psychiatry
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... -> Conductive hearing ... PagetsDisease #pathophysiology
Anorexia Nervosa: Signs and Symptoms
Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
episodes of binge-eating ... without binge eating ... psychological/behavioral features ... AnorexiaNervosa #pathophysiology ... signs #symptoms #psychiatry
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
combination of mental status ... Altered Mental Status ... following clinical features ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis