The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology ... #orthopedics #neurology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute ... RheumaticFever #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
, asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
Acute Otitis Externa ... hair pins) -> Injury ... #SwimmersEar #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... #OtitisMedia #pathophysiology ... symptoms #signs #peds
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Inflammation: Incr tissue injury ... Hydronephrosis, Acute ... chronic renal injury ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... #Immunization #peds ... #pediatrics #pathophysiology
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Ligament (ACL) Injury ... Feeling a "pop" • Acute ... AnteriorCruciateLigament #ACL #Injury ... #MSK #Sports #pathophysiology
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings

Parasomnias - Micro-arousal episodes during SWS ->
Intense activation of
Nightmares #Pediatrics #Peds ... #pathophysiology ... #symptoms #pharmacology