The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Dupuytren’s Disease: Pathogenesis and Clinical Findings
 • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
> Dupuytren's: benign ... Dupuytrens #Disease #Contractures ... #pathophysiology ... #msk
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... inflammation #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Pharmacology #Urology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Boutonniere Deformity: Pathogenesis and Complications
 • Hyperextension of DIP
 • Flexion of PIP
=> Boutonniere Deformity =>
joint => Premanent contracture ... Boutonniere #Deformity #pathophysiology ... #msk #rheumatoidarthritis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... stones #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Diffuse Systemic Sclerosis (Scleroderma)
 - Pulmonary Fibrosis -> Crackles, Abnormal CXR
 - Pulmonary Hypertension, Right Heart
Renal Failure - Mask ... Finger/hand/elbow contractures ... #Scleroderma #pathophysiology