The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology signs symptoms complications sle avascularnecrosis erythematosus excess gh growthhormone manifestations msk mucocutaneous musculoskeletal overproduction systemic
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Esp. humeral and femoral ... Myopathy (Also caused ... #Systemic #Lupus ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... visual acuity • Bitemporal ... Overproduction #diagnosis ... signs #symptoms #endocrinology
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
blood supply & the femoral ... ) • Multiple causes ... therapy - Lupus ... pathophysiology #diagnosis
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