The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis endocrinology pediatrics peds syndrome 21hydroxylasedeficiency 21ohd alzheimersdisease benign bph caudaequina dementia extraarticular geriatrics glftap hyperplasia keratoconus macroadenoma manifestations
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Mixed Urinary Incontinence ... Urgency Urinary Incontinence ... Incr PVR if a complication ... Pathophysiology #Signs ... #Symptoms #Urology
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... minor trauma #AnkylosingSpondylitis ... pathophysiology #diagnosis #signs ... #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... primitive reflexes, incontinence ... geriatrics #diagnosis #signs ... #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
lumbar spine Signs ... / Symptoms / Complications ... retention -> Overflow Incontinence ... pathophysiology #diagnosis #symptoms ... #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... PraderWilli #Syndrome #genetics
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Clinical Findings Genetics ... > Keratoconus Signs ... / Symptoms / Complications ... Ring • Munson's sign ... • Rizutti's Sign
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
A good mnemonic ... Signs / Symptoms ... / Complications ... endocrinology #mnemonic
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Bladder and bowel incontinence ... lung fibrosis #AnkylosingSpondylitis ... Manifestations #Complications ... pathophysiology #diagnosis #signs ... #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
emptying - Voiding Symptoms ... straining - Storage Symptoms ... Urgency, nocturia, incontinence ... Pathophysiology #Urology ... #Signs #Symptoms
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