The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... minor trauma #AnkylosingSpondylitis ... pathophysiology #diagnosis #signs
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive ... • Acute and chronic ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
> Keratoconus Signs ... / Symptoms / Complications ... Ring • Munson's sign ... • Rizutti's Sign ... pathophysiology #ophthalmology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incr PVR if a complication ... Pathophysiology #Signs ... #Symptoms #Urology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
damage & blindness Signs ... / Symptoms / Complications ... pathophysiology #ophthalmology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
findings Acute or Chronic ... pathophysiology #signs ... symptoms #diagnosis #otology
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... gum disease from chronic ... indication of chronic ... Symptoms related to complications ... weight Russell's Sign
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
-15, IL-17) -> Chronic ... , frequency Chronic ... Hydronephrosis, Acute or chronic ... Pathophysiology #Urology ... #Signs #Symptoms
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
the middle ear Signs ... / Symptoms / Complications ... Mastoiditis • Chronic ... pathophysiology #symptoms #signs ... #diagnosis #complications