The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Anterior Cord Syndrome ... • Central Cord Syndrome ... weakness and #Acute ... pathophysiology #signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... - Budd Chiari Syndrome ... pathophysiology #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis #Signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... geriatrics #diagnosis #signs
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... rubbing • Atopic diseases ... > Keratoconus Signs ... • Rizutti's Sign
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Carpal Tunnel Syndrome ... Cardiovascular disease ... Overproduction #diagnosis #signs
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... Syndrome • Crush ... allow fluid to disperse ... compartment pressure #Acute
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... trucking" • Acute ... ophthalmology #diagnosis #signs
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... • Non-specific Acute-phase ... Extra-articular signs ... pathophysiology #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... • The disease ... damage & blindness Signs ... Photophobia #Acute