The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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ovariancycle gh comparison diabeticketoacidosis diagnosis dka excess feedback feedbackloop follicularphase glftap hpoa hyperthyroidism hypothalamicpituitary lutealphase macroadenoma masseffects menstruation mnemonic overproduction
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
- FSH from pituitary ... - LH from pituitary ... not implant #MenstrualCycle ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
The Hypothalamic-Pituitary-Ovarian ... hypothalamus and anterior pituitary ... #MenstrualCycle ... #pathophysiology ... HypothalamicPituitary #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Signs / Symptoms ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
on the anterior pituitary ... for clarity) #MenstrualCycle ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained Early Follicular Phase (Days 0-5) • Granulosa cells
production by pituitary ... back on anterior pituitary ... #MenstrualCycle ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained • The LH surge can be thought
hypothalamus and anterior pituitary ... Ovarian Cycle #MenstrualCycle ... #OvarianCycle #pathophysiology ... #LutealPhase #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
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