The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis criteria psychiatry pathophysiology growthhormone pituitary 21hydroxylasedeficiency amsuicide antisocial aspd avoidant avpd borderline bpd corrupt cringes dependent dpd excess feedbackloop
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
experienced BPD Mnemonic ... the above with symptoms ... BPD #Borderline #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD ... pathophysiology #genetics #endocrinology
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
familiarity SPD Mnemonic ... #Schizotypal #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings • Difficulties with Activities - Initiation Of projects
themselves DPD Mnemonic ... DPD #Dependent #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings • Restraint - Shows excessive restraint in intimate
others AVPD Mnemonic ... AVPD #Avoidant #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings Work & lnterpersonal: • Home Life Troubles - Conflict
assault ASPD Mnemonic ... ASPD #Antisocial #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
of others NPD Mnemonic ... #Narcissistic #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
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