The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... #diagnosis #signs ... #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... excess: - ... #FeedbackLoop #endocrinology
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
experienced BPD Mnemonic ... BPD #Borderline #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #AMSUICIDE
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
assault ASPD Mnemonic ... ASPD #Antisocial #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #CORRUPT
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
familiarity SPD Mnemonic ... #Schizotypal #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #MEPECULIAR
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves DPD Mnemonic ... DPD #Dependent #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #RELIANCE
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
others AVPD Mnemonic ... AVPD #Avoidant #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #CRINGES
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings
 • Arrogant, Haughty Behaviors or Attitude - Often display
- Entitlement, Excess ... #Narcissistic #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #SPEEECIAL
Obsessive-Compulsive Personality Disorder (OCPD): Pathogenesis and Clinical Findings
 • Miserly - Lack of generosity when it
value OCPD Mnemonic ... ObsessiveCompulsive #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #SCRIMPER