The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis gh growthhormone msk acute caudaequina excess feedbackloop glftap hyperthyroidism injury macroadenoma masseffects mnemonic neurology orthopedics overproduction sideeffects sjogrens
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... production by the pituitary ... Signs/Symptoms: ... Pretibial myxedema #Primary ... Hyperthyroidism #endocrinology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
s Syndrome: Pathogenesis ... erythematosus (SLE) Signs ... / Symptoms: - ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... Signs / Symptoms ... #SideEffects #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... Bladder retention -> Primarily ... hemicord lesion -> Primarily ... pathophysiology #signs ... #symptoms #msk
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... / Symptoms / Complications ... reflexes) • Urinary ... #signs
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
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