The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis immunology signs symptoms hypersensitivityreaction allergic anticonvulsants classification complications definitions erythematosus gastrointestinal hypersensitivity management mechanism moodstabilizers pharmacology primary psychiatry reactions
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Patient's immune system ... Complications: • Acute ... conjunctivitis • Anaphylaxis ... #Immunology #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Vasculitis -> Acute ... - Budd Chiari Syndrome ... #Lupus #Erythematosus ... Complications #pathophysiology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... complexes • Ex: Systemic ... Lupus Erythematosus ... Stevens-Johnson Syndrome
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... symptoms in the acute ... #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... (PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... #Pathophysiology
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... (Acute) Additional ... provided, as well as allergy ... Ventolin inhaler #Anaphylaxis ... Treatments #Management #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Stevens-Johnson Syndrome ... , headache • Systemic ... #SideEffects #Pathophysiology
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