The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... and/or x-ray - CPPD ... #Pseudogout #CPPD ... #Disease #Signs ... Pathophysiology #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... ) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... Pathophysiology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Injury #Syndromes #diagnosis ... signs #symptoms #msk ... #orthopedics #neurology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... trucking" • Acute ... retinal edema caused ... ophthalmology #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... a stroke that caused ... pathophysiology #diagnosis ... stages #staging #msk
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... hearing loss, nausea ... signs #symptoms #diagnosis ... #otology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... pathophysiology #diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
- Sickle-cell disease ... ) • Multiple causes ... affected) - Acute ... pathophysiology #diagnosis