The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms chondrocalcinosis complications ophthalmology pseudogout adhesivecapsulitis avascularnecrosis centralretinalartery chronic crao frozenshoulder hypertensive injury mastoiditis neurology orthopedics otology pagetsdisease
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... trucking" • Acute ... retinal edema caused ... ophthalmology #diagnosis
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... #Disease #Signs ... Pathophysiology #Diagnosis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... BRB breakdown causes ... Hard Exudates • Occlusion ... ophthalmology #diagnosis
Priapism: Pathogenesis - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
Post-cavernosal venous occlusion ... e.g. sickle cell disease ... Pathophysiology #Urology ... #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Injury #Syndromes #diagnosis ... signs #symptoms #msk ... #orthopedics #neurology
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... #Disease #Signs ... Pathophysiology #Diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... a stroke that caused ... pathophysiology #diagnosis ... stages #staging #msk
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... hearing loss, nausea ... signs #symptoms #diagnosis ... #otology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... pathophysiology #diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
- Sickle-cell disease ... ) • Multiple causes ... affected) - Acute ... pathophysiology #diagnosis
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