The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Oscillation between mood states ... variability in disease ... maintain this state ... MoodDisorders #Diagnosis ... Signs #Symptoms #Psychiatry
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... a stroke that caused ... side) Second Stage ... pathophysiology #diagnosis ... #staging #msk
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Mental Status Exam ... (MSE) Note: The ... clothing, appears stated ... , the symptoms caused ... #psychiatry #diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... hypercoagulable state ... • Hematologic Disease ... retinal edema caused ... ophthalmology #diagnosis
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... are connected) Stage ... hearing loss, nausea ... signs #symptoms #diagnosis ... #otology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... Lots of fluid, takes ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Abnormal Osteoclasts cause ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... pathophysiology #diagnosis
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #Orthopedics #msk ... pathophysiology #diagnosis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
erosion and gum disease ... Sores, scars, calluses ... pathophysiology #diagnosis ... signs #symptoms #psychiatry
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
combination of mental status ... ingestion and most cases ... Altered Mental Status ... Pathophysiology #Psychiatry ... #Diagnosis #Signs