The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... etiology Signs/Symptoms ... endocrinology #symptoms ... #signs #diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic Hyperplasia ... Benign #Prostatic #Hyperplasia ... Pathophysiology #Urology ... #Signs #Symptoms ... #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... pathophysiology #signs #symptoms ... #orthopedics #neurology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
pathophysiology #signs #symptoms ... #diagnosis #otology
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
clinical findings Symptoms ... Hypersomnia - Hyperphagia ... season at work) Symptoms ... MoodDisorders #Diagnosis ... Pathophysiology #Signs #Symptoms
Hydrocele: Pathogenesis and Clinical Findings
Non-communicating:
 - Localized infection or trauma
 - Previous varicocelectomy or inguinal surgery
Pathophysiology #Signs #Symptoms ... #Diagnosis #Urology