The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... Hyperplasia: Pathogenesis ... chronic renal injury ... #Prostate #Pathophysiology ... #Urology #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... Akathisia • SSRI Withdrawal ... Syndrome - ... Serotonin #Inhibitors #Pathophysiology ... Diagnosis #Signs #Symptoms
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Note: Opioid withdrawal ... life-threatening (exceptions being ... combined with withdrawal ... #Opiate #Pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... Hyperplasia: Pathogenesis ... inflammation #BPH #Benign ... #Prostate #Pathophysiology ... #Pharmacology #Urology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... Diagnosis #Signs #Symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Allergic reaction -> Benign ... Stevens-Johnson Syndrome ... decr intake -> Withdrawal ... #SideEffects #Pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Complications: • Gonadal hypoplasia ... #genetics #pathophysiology
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Symptoms typically ... Alcohol withdrawal ... Seizures - Usually begin ... #Pathophysiology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine (BZD) withdrawal ... Asthma. or sense of being ... Benzodiazepine #BZD #withdrawal ... #pharmacology #pathophysiology ... diagnosis #signs #symptoms