The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs growthhormone msk orthopedics pituitary 21hydroxylasedeficiency 21ohd acute dislocation feedbackloop genetics glftap hyperthyroidism injury macroadenoma masseffects mastoiditis mnemonic neurology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... excess: - ... #FeedbackLoop #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder ... joint => Force exceeds ... bone -> Pain #Anterior ... Diagnosis #signs #symptoms ... #orthopedics #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
not always) the anterior ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings • Anterior ... Cord Syndrome -> Anterior ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Varicocele: Pathogenesis and clinical findings Primary: - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses - Inferior ... #Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
postauricular crease • Inferior ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
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