The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... almost always a benign ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... secretion from pituitary ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine ( ... Asthma. or sense of being ... BZD #withdrawal #pharmacology ... #pathophysiology ... diagnosis #signs #symptoms
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
life-threatening (exceptions being ... alcohol and/or benzodiazepines ... Symptoms can take ... The somatic symptoms ... Withdrawal #Opiate #Pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... stones #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs ... #Symptoms #Diagnosis