The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms pediatrics peds retinopathy syndrome alzheimersdisease caudaequina dementia diabetic diabeticfoot endocrinology erectile fecal genetics glftap macroadenoma masseffects mixed
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Fecal Incontinence ... Pathogenesis and Complications ... Diabetes) • Altered ... #Fecal #stool #Incontinence ... #geriatrics #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Signs / Symptoms / Complications ... Executive planning dysfunction ... primitive reflexes, incontinence ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Mixed Urinary Incontinence ... cystitis, UTI), diabetes ... Incr PVR if a complication ... #Mixed #Pathophysiology ... Signs #Symptoms #Urology
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
trauma, iatrogenic, diabetes ... hyperlipidemia, diabetes ... (penile artery diameter ... #Pathophysiology ... #Urology #Diagnosis
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... #Retinopathy #Diabetes ... #ophthalmology ... #diagnosis #complications ... #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... retention -> Overflow Incontinence ... bladder/bowel dysfunction ... Syndrome #MSK #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Obesity -> Type 2 diabetes ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology ... #complications ... #Diabetes
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... Hyperprolactinemia • Diabetes ... • Hypothalamic dysfunction ... mnemonic #GLFTAP #pathophysiology
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
-> Neovascular complications ... Prematurity #peds #pediatrics ... #pathophysiology ... #ophthalmology
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