The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
sudden +++ positive feedback ... for clarity) #MenstrualCycle ... #OvarianCycle # ... pathophysiology ... #Ovulation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
not implant #MenstrualCycle ... #OvarianCycle # ... pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
#MenstrualCycle ... #pathophysiology ... HypothalamicPituitary #endocrinology ... #feedback
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
Ovarian Cycle #MenstrualCycle ... #OvarianCycle # ... pathophysiology ... #LutealPhase #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
#UterineCycle #MenstrualCycle ... #OvarianCycle # ... pathophysiology ... #comparison #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
#MenstrualCycle ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology
Menstrual Cycle Physiology: the Uterine Cycle
The endometrium has receptors for ovarian hormones! Changes in structure and
fertilized) ovum #MenstrualCycle ... #OvarianCycle # ... pathophysiology ... #UterineCycle #endocrinology