The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... palpation - Vasculitic ... neurological findings #GiantCell ... #Temporal #Arteritis ... Pathophysiology #Diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Hemorrhages #GiantCell ... #Temporal #Arteritis ... Signs #Symptoms #diagnosis ... #Vasculitis
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... Erythematosus, Reactive Arthritis ... Reactions #Types #Classification ... #Diagnosis #Definitions
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... interstitial lung disease ... signs #symptoms #diagnosis
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Rheumatica and Cranial Arteritis ... Anemia of Chronic Disease ... Signs #Symptoms #Diagnosis ... #Vasculitis
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... in Rheumatoid arthritis ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... : - Coronary Arteritis ... #Criteria #Diagnosis ... Signs #Symptoms #Vasculitis
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
• Rheumatoid Arthritis ... underlying joint disease ... underlying joint disease ... Popliteal #BakersCyst #MSK ... signs #symptoms #diagnosis