The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology complications signs sle symptoms allergy systemic classification definitions gastrointestinal hypersensitivity hypersensitivityreaction immunology msk mucocutaneous musculoskeletal reactions type3 typeiii
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... • Ex: Systemic Lupus ... Erythematosus,
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Gastrointestinal Manifestations ... the pancreas, Vasculitis ... #Systemic #Lupus ... #Erythematosus
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Musculoskeletal Manifestations ... #Systemic #Lupus ... #Erythematosus
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... • Erythematosus ... HypersensitivityReaction #Allergy
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations
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