The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs complications sle erythematosus systemic comparison degenerative extraarticular gastrointestinal iga inflammatory jointdisease jointpain mucocutaneous musculoskeletal ra rheumatoidarthritis versus
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Musculoskeletal Manifestations ... Osteonecrosis Esp ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Gastrointestinal Manifestations ... the pancreas, Vasculitis ... #Systemic #Lupus ... pathophysiology #signs #symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... and ankles) #HSP ... #IgA #Vasculitis ... #HenochScholeinPurpura ... Diagnosis #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... pathophysiology #signs #symptoms
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Rheumatoid arthritis, Lupus ... Extra-articular manifestations ... affects the knee hip ... Comparison #Versus #MSK
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