Kenya A Lovett @kenyaalovett on GrepMed

Keeping up with Atypical Antipsychotics (aka second generation antipsychotics - SGA). I'll be posting series of topics focused on this class of drugs, including their receptor activity/pharmcodynamic and safety profiles. So, here's to Part 1 - Types of Atypical Antipsychotics: simplified way of remembering their names by grouping into: "DONEs", "PINEs", "PIPs”and "RIP”. #AntipsychoticDrugs #AtypicalAntipsychotics #SGAs #Antipsychotics #BehavioralHealth #MentalHealth #Psychiatry #Pharmacy #Pharmacology #Medication #PrimaryCare #FamilyMedicine #MedEd #FOAMed #InfoGraphic #Clinical #Pharmacotherapy

ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the following ACEIs: benazepril, enalapril, fosinopril, moexipril, quinapril, and ramipril. Monitor BP, potassium, and renal function. #ACEInhibitor #ACEIs #Dosing #Conversion #Pharmacology #Hypertension #Management #PrimaryCare #Comparison #Table

Systemic Glucocorticoid Dose Equivalents. Note: approximate equivalent dose is based on anti-inflammatory potency. Fludrocortisone is not included because of its high degree of mineralocorticoid activity and minimal degree of anti-inflammatory activity, therefore not considered interchangeable with listed glucocorticoids. Also, dexamethasone is commonly used to prevent CINV (chemotherapy induced nausea and vomiting) and PONV (postoperative nausea and vomiting). #Corticosteroid #Steroid #Conversion #Table #Dose #Equivalents #Pharmacology

Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take a quick review of azithromycin since it is being used in combination with hydroxychloroquine as one of the investigational treatments for COVID-19… - Note azithromycin has a long half-life of about 68 hrs (or more) and is an inhibitor of P-glycoprotein/ABCB1 so watch for potential DIs with colchicine, dabigatran, edoxaban, ranolazine, etc. Also, don't forget about increased QT prolongation risk when used in combo with chloroquine or hydroxychloroquine‼️ For Educational Purposes Only #Azithromycin #COVID19 #Pandemic #Treatment #Coronavirus #InfectionDiseases

Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. For lithium, target levels vary depending on treatment indication. Therapeutic range for digoxin in heart failure is lower (0.5 - 0.8 ng/mL) due to an increased risk of mortality at a higher level. *For Educational Purposes Only* #DrugLevels #Therapeutic #Ranges #Toxicology #Pharmacology #Diagnosis #Table #Monitoring

Most ophthalmic drop caps are color coordinated with their pharmacologic class. Here is a color-coded chart with list of commonly prescribed ophthalmic drops. (note: this is not a complete list). #Ophthalmic #EyeDrops #Color #Classification #DrugClass #Caps #gtt #Pharmacology #Ophthalmology

With the recent publication of the FDA Guidance on alcohol-based hand sanitizer compounding, I thought to post the 2 formulations that are consistent with both the FDA and WHO recommendations. FDA is also encouraging pharmacists to compound these in light of current COVID-19 pandemic and hand sanitizer shortage. *For Educational Purposes Only* #COVID19 #Coronavirus #Compounding #Pharmacology #HandSanitizer

Anticoagulation Review. There are other bleeding risk assessment tools, but HAS-BLED is more commonly used. HTN defined as having SBP greater than 160 mmHg. Bleeding includes history or predisposition. Examples of drugs that increase bleeding include antiplatelets or NSAIDs and alcohol use of having more than 8 servings/week. *For Educational Purposes Only* #Anticoagulation #Anticoagulant #Bleeding #Risk #Tool #Assessment #Cardiology #SideEffects #Symptoms #Signs

Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take a quick review of azithromycin since it is being used in combination with hydroxychloroquine as one of the investigational treatments for COVID-19… Note azithromycin has a long half-life of about 68 hrs (or more) and is an inhibitor of P-glycoprotein/ABCB1 so watch for potential DIs with colchicine, dabigatran, edoxaban, ranolazine, etc. Also, don't forget about increased QT prolongation risk when used in combo with chloroquine or hydroxychloroquine‼️ #Azithromycin #Zithromax #Macrolides #InfectiousDiseases #COVID19 #Coronavirus #Treatment #Management #Pharmacology #DrugInteraction #Pandemic

Ivermectin. Old anti-parasitic agent making a comeback with recent headlines from in-vitro study that showed antiviral activity against SARS-CoV-2, the virus causing COVID-19. In preparation for another wave (like chloroquine/HCQ), here is a quick overview of ivermectin… #COVID19 #Coronavirus #SARS-CoV-2 #Pandemic #Outbreak #InfectiousDiseases #CriticalCare #EmergencyMedicine #Pharmacology #Treatment #Virus #Antiviral #Management #Ivermectin #Antiparasite