montserrat vergara @monvergara98 on GrepMed

Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3) Hypocomplementemia (C3 and/or C4) Therapeutic management 1st-line therapy - Hydroxychloroquine, colchicine or disulone 2nd-line therapy - GCs <0.5 mg/kg/day Refractory and/or relapsing - Azathioprine, MMF, cyclophosphamide Alternative agents - Rituximab, anti-IgE, anti-IL-1 Dr. Benjamin Terrier @TerrierBen #Hypocomplementemic #Urticarial #Vasculitis #HUV #Diagnosis #Management #Rheumatology

Diuresis in Critical Care - Achieving a Negative Fluid Balance Advantages Of A Negative Fluid Balance: • Volume overload is very common in the later (e.g. de-escalation) phases of critical illness. Achieving a negative fluid balance is key to liberation from MV, mobility, & ultimate recovery. • In people with sepsis, AKI, or who are post-op, risk of mortality increased by 1.19x per liter of positive fluid balance. MINIMIZE INs: • USE FLUIDS PARSIMONIOUSLY IN RESUSCTIATION • SWITCH IV TO PO • USE HIGH CONCENTRATION MEDICATIONS • AVOID MAINTENANCE FLUIDS • REMOVE UNECCESARY MEDS MAXIMIZE OUTs: • Start with LOOP DIURETICS which are short acting and rapidly titrated to achieve UOP • Add a THIAZIDE to augment diuresis, address diuretic resistance, & to correct hyponatremia • Add a SPIRONOLACTONE (or ENaC INHIBITOR) to normalize Potassium homeostasis especially in high aldosterone states (CHF, Cirrhosis) • Add ACETAZOLAMIDE to correct a contraction metabolic alkalosis & further augment diuresis. • ULTRAFILTRATION is indicated for removal of fluids in volume overloaded patients who are refractory to diuresis. - Timing is controversial. Early nephrologv consult may be associated with improved survival in AKI. - Nick Mark MD @nickmmark #Diuresis #Negative #Fluid #Balance #management #criticalcare

Diagnostic Algorithms for Microcytic, Normocytic and Macrocytic Anemia #Microcytic #Normocytic #Macrocytic #Anemia #Algorithm #Comparison #Diagnosis

An Algorithm for the Evaluation and Management of Cardiac Arrest with Ultrasonography - Dr. Tom Fadial https://twitter.com/thame #CardiacArrest #Algorithm #POCUS #Evaluation #Diagnosis #Management #Ultrasound #CriticalCare

To Board or Not To Board? Infographic by Tommaso Scquizzato (@tscquizzato) based on this review on RebelEM https://rebelem.com/spinal-immobilization-in-trauma-patients/ #EMS #SpinalImmobilization #Trauma

Takotsubo Cardiomyopathy - Summary Sheet • Definition • Epidemiology • Pathogenesis • Presentation • Management by Dr. Lizzy Hastie @LizzyHastie #Takotsubo #Cardiomyopathy #diagnosis #management #cardiology #summary

Coombs Test - Direct vs Indirect #Diagnosis #Testing #Coombs #Direct #Indirect #Hemolytic #Anemia

Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV • Parasitic- Babesia Immunodeficiency • Hematopoietic stem cell transplant • Solid organ Transplant Lymphoproliferative • CLL • Non-Hodgkin Lymphoma Autoimmune • Lupus • Rheumatoid arthritis • Scleroderma • Ulcerative colitis • Granulomatosis with polyangiitis Drug Exposure • Antibiotics- eg penicillin, cephalosporins • NSAIDs/antipyretics- e.g. diclofenac, acetaminophen • Anticancer agents- eg fludarabine, cisplatin, ipilimumab • Others- eg. alpha-methyldopa COLD AHA - Primary - Idiopathic - Secondary Lymphoproliferative • CLL • Non-Hodgkin Lymphoma - Secondary Infectious • EBV • Viral PNA • Mycoplasma Nikita Deshpande @NikitaSonaliyaD #Autoimmune #Hemolytic #Anemia #AIHA #Diagnosis #Differential #Algorithm

Algorithm for the Diagnosis and Workup of Hemolytic Anemia By Dr. Kylie Adamek @KylieAdamek #Hemolytic #Anemia #Algorithm #Differential #Diagnosis #Workup #Hematology #Hemolysis

Algorithm for the Management of Severe Traumatic Brain Injury (TBI) #Management #NSG #TBI #Traumatic #Brain #Injury #TraumaticBrainInjury #Algorithm #Mannitol #ICP #CPP #Ddxof