reem al saadi @REEMALS21
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Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... typically prolong PT ... antibody Prolonged PT ... #Abnormal #PT
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #Abnormal #PT
Approach to ECGs - Syncope Syndromes
Electrolytes
 • ↑K - brady, peak T, wide QRS, no P,
Syncope #Syndromes #ECG ... #EKG #Checklist
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... Vascular occlusion (e.g ... related to kidney e.g ... disease or drugs e.g ... AIN) • Drugs (e.g
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
selected cases: INR/PT ... function test, ANA (e.g
Approach to ECGs - Ischemia
MI = Biomarkers + ECG or echo/angiogram findings
Pathologic Q - 1/3 height
= Biomarkers + ECG ... #Ischemia #ECG ... #EKG #diagnosis
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
bradyarrhythmia #ECG ... #EKG #diagnosis
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Osm <100 mOsm/kg ... Osm 100-200 mOsm/kg ... Osm 300-500 mOsm/kg
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Granulomatous Disorders (eg
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
• Infection eg