Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Thrombosis vs Arterial ... - Differential Diagnosis ... Fat Emboli ARTERIAL ... pathophysiology #hematology ... #differential #diagnosis
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... - Differential Diagnosis ... - TMA: TTP - Arterial ... #Differential #Diagnosis ... #clots #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... Diagnosis: • hemolytic ... Monoclonal IgM ... hemolytic #anemia #hematology ... #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... abnormal intact monoclonal ... : • Serum IgM monoclonal ... #Significance #hematology ... #diagnosis #oncology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
- Differential Diagnosis ... Stroke Volume / Arterial ... less compliant arteries ... Differential Diagnoses ... #Differential #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... 10 mm + pus • Material ... Bacterial folliculitis ... #Differential #Diagnosis ... #Dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... gangrenosum • Bacterial ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Narrow Complex Tachycardias (Simplified)

Irregular Narrow Complex Tachycardia:
 1. Atrial fibrillation
	- Usually the correct answer
 2. Multifocal
Atrial fibrillation ... Multifocal Atrial ... Atrial flutter ... (Ectopic) Atrial ... #differential #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulins: - Single monoclonal ... - Composed of monoclonal ... Labs/Diagnosis: ... Cryoglobulins #diagnosis