Ravi Singh K @rav7ks
1.2M 757 370
Academic Hospitalist and Associate Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Hopkins Medicine Clerkship Site Director, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... Differential #Diagnosis #Algorithm ... #Pathophysiology ... #Nephrology #Chloride
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... Pathophysiology: ... Bland urine (no casts ... Exclude other AKI causes ... Syndrome #Hepatology #Nephrology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... nephrocalcinosis • CPPD ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Phosphate is a cause ... phosphorus is seen in COPD ... patients with COPD ... respiratory #hypoxia #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... management #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... • 75-90% of cases ... monophasic Pathophysiology ... • Infectious causes ... diagnosis #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... the underlying cause ... with AEDs until cause ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... Lateral #Sclerosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Non-compressive Spinal Cord Causes ... disorders #diagnosis #neurology ... differential #algorithm
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Management #treatment #neurology