Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... developing active infection ... IGRA/QuantiFERON-TB ... age ACTIVE TB ... LatentTB #ActiveTB #InfectiousDiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... hemorrhage • Treatment ... continue antibiotic treatment ... several months of treatment ... westermani • Other: TB
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Factors For NTM Infections ... infections • ... Kansasii: • Mimics TB ... differential #diagnosis #infectiousdiseases
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
and bacterial infections ... Pyogenic/focal infection ... • Lymphoma • TB ... Night Sweats: • TB ... Brucellosis • Liver or lung
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
: • Recurrent infection ... : TB, NTM, PNA ... in the adjacent lung ... of the affected lung ... mycobacteria Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
(<100), except TB ... TB - Lymphadenitis ... cryptococcal or TB ... survival) • TB ... for TB meningitis
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... infiltrates, mimicking TB ... cough, myalgia • Lung ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
associated with infection ... Cerumen impaction Infectious ... (90%), Fungal infections ... subdural hematoma, lung ... Otalgia #Ear #Pain #Otology