Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV ... dementia Pathophysiology ... Treatment: • HAART ... treatment • Cognitive ... reversible • HAND is also
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in HIV ... Antimicrobial treatment ... • Symptoms: AMS ... symptoms such as ... opportunistic #InfectiousDiseases
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
• Presents as ... symptoms • >50,000 HIV ... -1 and HIV-2 • ... HIV-1 RNA viral ... antibody test) Treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Infection (Viral- HIV ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Summary #causes #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... complete paralysis of all ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
prostaglandins as ... PATHOPHYSIOLOGY: ... Rigors #Bacteremia #Pathophysiology ... #InfectiousDiseases
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... diagnosis column Treatment ... motor neurons - IV
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Active TB: • HIV ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... hemorrhage • Treatment ... continue antibiotic treatment ... several months of treatment ... causes #management #treatment
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Other - ALS, Dementia ... Barium swallow is also ... Barium swallow is also ... disorder → EGD Treatment ... Diagnosis #Management #gastroenterology