Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Noncardiogenic Pulmonary ... Framework NCPE Pathophysiology ... Noncardiogenic pulmonary ... respiratory distress syndrome ... (ARDS) • Opioid
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Summary Acute AIDP ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Etiology: • Pathophysiology ... epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
host): • Chronic pulmonary ... Histoplasmosis Treatment ... Mucormycosis Treatment ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... be present: • AIDS ... Lymphadenitis, pulmonary ... #Inflammatory #Syndrome
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive ... disorder #dementia #AIDS
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... organizing pneumonia, ARDS ... respiratory distress syndrome ... pneumonia - Pulmonary ... macrophages Treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... search for and treatment ... Pathophysiology ... Treatment Approach ... Diagnosis #Management #Hematology