ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the following ACEIs: benazepril, enalapril, fosinopril, moexipril, quinapril, and ramipril. Monitor BP, potassium, and renal function.
#ACEInhibitor #ACEIs #Dosing #Conversion #Pharmacology #Hypertension #Management #PrimaryCare #Comparison #Table
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
- General - From asymptomatic to myxedema coma, “Like everything is slowed down”
• Low exercise tolerance
• Hyperlipidemia
• Cold intolerance
• Weight gain (modest)
- Neuro
• Depression
• Memory loss
• Fatigue
- Face/Neck
• Hair is coarse, brittle and is lost
• Thinning of lateral 1/3 of eye brows
• Puffy Face
• Enlarged tongue
• Hoarseness
• ± Goitre
- Cardiovascular
• bradycardia
• cardiomegaly
• pericardial effusion
• hypertension
- GI
• Constipation
- Gu:
• Menorrhagia
- Skin
• Skin is dry, coarse, thick, cold, pale
- Muscles
• Weakness, cramps
• Tendon Reflex Delay (relaxation phase)
Hyperthyroidism:
- General “Like running a marathon all the time”
• Appear to have high energy but are fatigued
• poor exercise tolerance
• Heat intolerance
• Weight loss (despite appetite)
- Neuro:
• Nervousness
• Restlessness
• Insomnia
• Tremour
• Increased Reflexes
- Face/Neck
• ophthalmopathy
ocular changes (periorbital swelling, lid retraction and lid lag, stare and infrequent blinking)
infiltrative (proptosis/exophthalmos, increased edema of lids and conjunctiva, chemosis, ophthalmoplegia)
• ± Diffuse goitre
• Bruit (when osculating over thyroid)
- Cardiovascular
• Palpitations, Afib
- GI
• Diarrhea
- Gu:
• Infertility, amenorrhea
- Skin
• Sweating
• Warm, moist skin
• Dermatopathy
Ø Hands: Acropachy
Ø Legs: “pretibial myxedema
- Amy Chung, MD, MSc @AmyChung
#Hypothyroid #Hyperthyroid #Symptoms #Signs #Diagnosis #endocrinology #Hypothyroidism #Hyperthyroidism
Hypothyroidism – symptoms and signs.
Symptoms:
Tiredness/malaise,
Weight gain,
Anorexia,
Cold intolerance,
Poor memory,
Change in appearance,
Depression,
Poor libido,
Goitre,
Puffy eyes,
Dry brittle unmanageable hair,
Dry coarse skin,
Arthralgia,
Myalgia,
Muscle weakness/Stiffness,
Constipation,
Menorrhagia or
oligomenorrhoea in women,
Psychosis,
Deafness
Signs:
Mental slowness,
Psychosis/dementia,
Ataxia,
Poverty of movement,
Deafness,
Peaches and cream complexion,
Dry thin hair,
Loss of eyebrows,
Hypertension,
Hypothermia,
Heart failure,
Bradycardia,
Pericardial effusion,
Cold peripheries,
Carpal timel syndrome,
Oedema,
Periorbital oedema,
Deep voice,
(Goitre),
Dry skin,
Mild obesity,
Myotonia,
Muscular hypertrophy,
Proximal myopathy,
Slow-relaxing reflexes,
Anaemia
#Hypothyroid #Features #Signs #Symptoms #Diagnosis #PhysicalExam #Endocrinology
Group A Strep Pharyngitis, also known as Strep Throat.
In addition to symptomatic presentation, a rapid antigen detection test can be done at point-of-care with a throat swab. This is a great expanding area for pharmacists in the retail/community setting too! If positive, no culture is needed, and patients should be prescribed one of the treatment options recommended by IDSA. That's because this test is highly SPECIFIC (see older post regarding specificity vs sensitivity for a helpful stats review). If the throat swab is negative in children or adolescents, it's recommended to have a follow-up culture to be certain. ----
There are options for patients with penicillin allergies as well, but let's be sure these patients actually have a true penicillin allergy! Large majority of patients with "penicillin allergy" listed in their chart do not actually have a true allergy. This is another great intervention for pharmacists - penicillin allergy testing!
Jarred Prudencio, PharmD - https://www.instagram.com/ambcarerx
#GroupA #Strep #Pharyngitis #StrepThroat #Management #Treatment