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Alexis Anderson
@ananderson2
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diagnosis
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CT Coronary Angiography Indications - Appropriateness Criteria @StanfordChiefs #CCTA #Appropriateness #criteria #indications #cardiology #radiology #CTA #Cardiac
Antidepressant Comparison Chart - Dosing and Major Side Effects Fluoxetine Sertraline Citalopram Escitalopram Paroxetine Fluvoxamine Venlaxafine Duloxetine Mirtazapine Bupropion by Dr. Sam Jackson via Dr Poorman @DrPoorman #Antidepressant #Comparison #Chart #psychiatry #medications #dosing
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses facilitating GABA-mediated chloride ion channel opening frequency • enhance membrane hyperpolarization - Dose-dependent depressant effects on the CNS including sedation and relief of anxiety • amnesia • hypnosis • anesthesia • coma • and respiratory depression Barbituates: - Bind to specific GABA-A receptor subunits at CNS neuronal synapses facilitating GABA-mediated chloride ion channel duration • enhance membrane hyperpolarization - Dose-dependent depressant effects on the CNS including sedation and relief of anxiety • amnesia • hypnosis • anesthesia • coma and respiratory depression • dose-response relationship than Newer Hyponotics: - Bind selectively to a subgroup of GABAA receptors, acting like benzodiazepines to enhance membrane hyperpolarization - Rapid onset of hypnosis with few amnestic effects or day-after psychomotor depression or somnolence Melatonin Receptor Antagonists: - Activates MT1 and MT2 receptors in suprachiasmatic nuclei in the CNS - Rapid onset of sleep with minimal rebound insomnia or withdrawal symptoms Orexin Antagonists: - Blocks binding of orexins, neuropeptides that promote wakefulness - Promotes sleep onset and duration 5-HT-Receptor Agonist: Mechanism uncertain: - Partial agonist at 5-HT receptors but affinity for receptors also possible - Slow onset (1-2 weeks) of anxiolytic effects • minimal psychomotor impairment—no additive CNS depression with sedative-hypnotic drugs #Sedative #Hypnotic #Drugs #medications #pharmacology #comparison #table
Central Nervous System Pharmacology - Somatic and Autonomic Receptors Somatic • Rocuronium -> Non-depolarizing (reversible competitive inhibitors) • Succinylcholine -> Depolarization • Neostigmine - blocks action AchE = increases the levels of Ach (reversal of nondepolarizing agents) • Atropine -> reversible competitive antagonist (anti- cholinergic) Autonomic • Parasympathetic “Rest and Digest” - Ach -> Nicotinic Receptor -> Ach -> Muscarinic Receptor • Sympathetic “Fight or Flight” - Ach -> Nicotinic Receptor -> NE -> Adrenergic Receptor • Sympathetic Innervation of Adrenal Medulla - Ach -> Adrenal Medulla Nicotinic Receptor -> Epinephrine released into blood -> Adrenergic Receptor - Amy Chung, MD, MSc @AmyChung #Central #NervousSystem #CNS #Somatic #Autonomic #Receptors #Pharmacology
Peripheral Nervous System Disorders 1 Anterior Horn Cell 2 Spinal Roots and Nerves 3 Peripheral Nerve—Mono-neuropathy 4 Peripheral Nerve— Polyneuropathy 5 Neuromuscular Junction 6 Muscle #Peripheral #PNS #Lesions #Nerve #Neuropathy #Neurology #Localization #Diagnosis
Check out this cranial nerves #chart for #assessment in nursing! Assessment of the cranial nerves provides insightful and vital information about the patient’s nervous system. There are 12 cranial nerves that are often forgotten by nurses, so with that in mind, here’s a free assessment form that you can use!
Status Epilepticus Algorithm #Pharm #Management #Peds #Status #Epilepticus #Refractory #Seizures #PEMSource
Epilepsy Seizure Types - Generalized vs Focal Generalized Seizures - Absence seizures - Myoclonic seizures - Tonic seizures - Tonic-clonic seizures - Atonic seizures #Generalized #Focal #Seizures #Types #Classification #Neurology #Differential #Diagnosis
Stroke Territories and Resulting Syndromes and Effects #Stroke #CVA #Territories #Territory #Syndromes #Effects #Diagnosis #Localization
Reduction of Posterior Elbow Dislocation #Elbow #Dislocation #Reduction #Posterior #clinical #video #msk #sports #orthopedics #physicalexam
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