Pathnologic @pathnologic
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Path Geek - All things #pathology
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A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... promyelocytic leukemia (APL ... In addition to APL ... ) t(8;21), AML with ... Clinical #Path #BloodSmear
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... Clinical #Path #BloodSmear ... Rods #AuerRods #AML
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... iron deficiency anemia ... Clinical #Path #BloodSmear
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
iron deficiency anemia ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... Clinical #Path #BloodSmear
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
seen in hemolytic anemias ... microangiopathic hemolytic anemia ... Clinical #Path #BloodSmear
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
/megaloblastic anaemia ... Pathology #Microscopy #BloodSmear
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML