Pathnologic @pathnologic
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A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... promyelocytic leukemia (APL ... In addition to APL ... #Clinical #Path ... Rods #AuerRods #APL
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical ... #Smear
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Microscopy ... Rods #AuerRods #AML
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Elliptocyte
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Dacrocytes
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
another peripheral blood ... smear demonstrating ... iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear #Anemia
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Codocytes
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Myeloid Leukemia (AML ... Prolymphocytes #Smear ... Pathology #Microscopy #Clinical ... #Blood
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... Clinical conditions ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Schistocytes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
This smear was from ... and hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Spherocytes