Pathnologic @pathnologic
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Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... extensive rouleaux formation ... #rouleaux #formation ... Clinical #Smear #Hematology ... #Pathology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... MGUS #Clinical #Pathology ... #Hematology #Smear
Dysplasia in Myelodysplastic Syndrome 
 - 
Dysgranulopoiesis 
 - Dyserythropoiesis 
 - Dysmegakaryopoiesis 

#Dysplasias #MDS #Myelodysplastic
Myelodysplastic Syndrome ... Myelodysplastic #Syndrome ... #Pathology #Hematology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Cells #Clinical #Pathology ... Smear #Microscopy #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... #Clinical #Pathology ... Microscopy #Rouleaux #Formation ... #Hematology