Pathnologic @pathnologic
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Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... #Auer #Rods #Acute ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
mucosal-dominant Pemphigus ... mucosal #dominant #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... MGUS #Clinical #Pathology ... #Hematology #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case of acute ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
extensive rouleaux formation ... leukemia #rouleaux #formation ... Clinical #Smear #Hematology ... #Pathology
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Acute Graft versus ... Host #disease #Pathology ... #Microscopy #Dermatology
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
good example of Pemphigus ... SGottesmanMD #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... #Clinical #Pathology ... Microscopy #Rouleaux #Formation ... #Hematology