Pathnologic @pathnologic
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Path Geek - All things #pathology
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A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia (APL ... In addition to APL ... ) t(8;21), AML with ... #Clinical #Path ... #Smear #Microscopy
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Smear
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Microscopy ... Rods #AuerRods #AML
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
normal peripheral blood ... smear indicates ... appearance of red blood ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
another peripheral blood ... smear demonstrating ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Myeloid Leukemia (AML ... Prolymphocytes #Smear ... Peripheral #Pathology #Microscopy ... #Clinical #Blood
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... #Clinical #Path ... #Blood #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... #Clinical #Path ... #Blood #Smear #Microscopy
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... wherein normal blood ... #Smear #Microscopy ... #Rouleaux #Formation ... #Hematology