Pathnologic @pathnologic
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Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... with extensive rouleaux ... PlasmaCell #leukemia #rouleaux ... formation #Clinical #Smear ... #Hematology #Pathology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... MGUS #Clinical #Pathology ... #Hematology #Smear
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image).

Dutcher bodies are round,
Neoplastic plasma ... bodies are round, agranular ... appear somewhat granular ... #Intranuclear #Pathology ... #Clinical #Smear
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... occurs when the plasma ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... #Parvovirus #Pathology ... #Smear #Microscopy ... #Hematology #Clinical
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... leukemia #APL #APML #Pathology ... #Hematology #Clinical ... #Smear