Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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hepatology diagnosis pbc algorithm management treatment causes differential indications albumin dili druginduced hbv hepatitisb hepbv liver liverinjury severe
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... T-cell mediated BEC injury ... Cholestasis #PBC #Primary ... #Biliary #Cirrhosis
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... biliary obstruction ... Drug-Induced liver injury ... Hemochromatosis - Primary ... biliary cholangitis
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... with PBC #PBC #Primary ... #Biliary #Cirrhosis
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary ... biliary cirrhosis ... Differential #Hepatology #Cirrhosis
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 Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Benign/malignant biliary ... obstruction, Primary ... biliary cholangitis ... , Primary sclerosing ... dechallenge • Acute
Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm #Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... Algorithm #Primary ... #Biliary #Cirrhosis
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ascites removed • Acute ... kidney injury ( ... Indications #Management #Cirrhosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Family history of cirrhosis ... or fibrosis • Cirrhosis ... immunosuppression • Acute ... with severe liver injury ... > 3 mg/dL) or acute
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... disease #PBC #Primary ... #Biliary #Cirrhosis
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