Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel ... Syndrome (IBS) - ... functional somatic syndromes ... Pregabalin #IBS #Irritable ... #Bowel #Syndrome
Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
- Hepatorenal Syndrome ... Pathophysiology #hepatology #liver
Carcinoid Syndrome - Pathophysiology, Signs and Symptoms
Symptoms: Flushing, diarrhea, palpitations, bronchospasm
Complications: Carcinoid heart, mesenteric fibrosis, pellagra,
Carcinoid Syndrome ... neuropsychological disorders ... #Carcinoid #Syndrome
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Alcohol-related liver ... cholangitis Consider liver ... Hepatic vascular disorder ... #DrugInduced #Liver
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... the pattern of liver ... presence of metabolic syndrome
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
symptoms, elevated liver ... is >1,000 μg/L, liver ... A liver biopsy can ... with elevated liver ... and hematologic disorders
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
paracentesis (>5 liter ... ) - 8g per liter ... • Hepatorenal syndrome
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome
Ileal Pouch Disorders - Differential Diagnosis
 • Surgical/Mechanical: Anastomotic leak, Pelvic sepsis, Sinus, Fistula, Strictures, Efferent
Ileal Pouch Disorders ... Efferent limb syndrome ... • Functional: Irritable ... pouch syndrome, ... #Ileal #Pouch #Disorders
Rome IV Criteria for the Irritable Bowel Syndrome.

#Diagnosis #PrimaryCare #IBS #IrritableBowelSyndrome #RomeIV #Criteria
Criteria for the Irritable ... Bowel Syndrome.