Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... Infections #Cirrhosis ... #Pathophysiology ... #hepatology #liver
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... paracentesis (>5 liter ... ) - 8g per liter ... Indications #Management #Cirrhosis ... #treatment #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Gl History - Cirrhosis ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver
Hepatocellular Carcinoma (HCC) in Cirrhosis - Management Algorithm

Very early (0) - Single <2 cm, Preserved liver
Carcinoma (HCC) in Cirrhosis ... cm, Preserved liver ... cm, Preserved liver ... HCC, End-stage liver ... Carcinoma #HCC #Cirrhosis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... infection with severe liver ... mg/dL) or acute liver
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Functions of the Liver ... Synthesis #Pathophysiology ... #Functions #Liver
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... Primary biliary cirrhosis ... Nonalcoholic fatty liver ... Differential #Hepatology #Cirrhosis
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Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... - Pathophysiology ... relative with PBC Pathophysiology ... Primary #Biliary #Cirrhosis ... #Pathophysiology
Screening and surveillance of varices in patients with cirrhosis. 

- No for screening need if platelets
patients with cirrhosis ... platelets >150 Liver
The Gastroenterology Consult Primer
Guide to Calling a GI Consult
HPI:
 - Start with reason for consult
consult - I-liner ... Focus on prior GI/Liver ... last meal - Treatment ... GregoryTBrennan #Liver