Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Pulmonary Function Testing (PFT) Interpretation Algorithm

Restrictive Lung Disease:
 • Chest wall or neuromuscular disorders
 • Interstitial
Pulmonary Function ... Algorithm Restrictive ... Lung Disease Obstructive ... #Testing #PFT # ... #diagnosis #asthma
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... Anemia #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Algorithm Features ... of hematologic ... #Differential #Diagnosis ... #Algorithm #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management Algorithm ... hemosiderin, Hepatic function ... #Management #Algorithm ... #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
- Differential Diagnosis ... Algorithm aPTT ... aPTT #PT #INR #Algorithm ... #Hematology #differential ... #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... → Refer to hematology ... #Differential #Diagnosis ... #Algorithm #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
- Differential Diagnosis ... Algorithm Decreased ... #Differential #Diagnosis ... #Algorithm #hematology
Approach to Von Willebrand disease (VWD)

By Matthew Ho, MD PhD @MatthewHoMD

#VWD #Von #Willebrand #VonWillebrand #disease #hematology
VonWillebrand #disease #hematology ... #algorithm #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... - Differential Diagnosis ... #Anemia #MCV #Algorithm ... #Differential #Diagnosis ... #hematology