45 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... 3. ... Signs / Symptoms ... #Anaphylaxis #pathophysiology ... immunology #diagnosis #signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
spontaneous within 3- ... 6 months of symptom ... MeralgiaParesthetica #MSK #pathophysiology ... differential #diagnosis #signs ... #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... involvement (type 2 and 3) ... Disease #Diagnosis #Signs ... #Symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #symptoms
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... Conditioning regimen Signs ... /Symptoms: Typically ... EBV viral load, signs ... Lymphoproliferative #Disorders #oncology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... /symptoms of active ... decreased reflexes Pathophysiology ... should be done in ALL
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... • Diagnosis: >3 ... symptoms, or> 1 ... management #hematology #oncology
The Gastroenterology Consult Primer
Guide to Calling a GI Consult
HPI:
 - Start with reason for consult
I-liner summary - Symptoms ... lipase PMH: - Focus ... : Cardiac/pulm/oncologic ... Antiplatelet & AC
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... have fever - ACS ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... satiety, bendopnea. 3. ... systolic dysfunction 3. ... Pharmacology: • ACE