17 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... internal organs 3 ... skin thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Symptoms: Fatigue ... quadrant discomfort Signs ... Diagnose PBC if 2/3 ... criteria are met ... gp210/sp100) 3.
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Disease Systemic ... the chest/trunk Symptoms ... weeks or longer 3. ... #AOSD #diagnosis ... #rheumatology #
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Tropheryma whipplei Symptoms ... and Signs: 1. ... Weight loss (90%) 3. ... #diagnosis #algorithm
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Lung involvement 3% ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... if evidence of systemic ... purposes of this algorithm ... clinical and lab signs ... #Incomplete #Algorithm
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3.
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... sx + signs/sx of ... elicited after 2-3 ... them, but urgent rheumatology ... GCA #Temporal #Signs
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Summary Diagnostic Criteria ... , signs, and complications ... • Treatment algorithms ... von Willebrand disease ... Summary #treatment #hematology