62 results
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... T lymphocytes also ... #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Acne • Coarse features ... Cardiovascular disease ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... involvement (type 2 and 3) ... #Diagnosis #Signs ... #Symptoms
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
rare, gestational diseases ... pituitary can also ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
‘Leakage’ symptoms ... as thyroid is damaged ... destruction 3. ... Hashitoxicosis #Hashimotos #Endocrinology ... #Diagnosis #Pathophysiology
Wilson's Disease - Pathogenesis and Clinical Features

#Wilsons #Disease #Pathophysiology #signs #symptoms #diagnosis #copper
Wilson's Disease ... Pathogenesis and Clinical Features ... #Pathophysiology ... #signs #symptoms ... #diagnosis #copper
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Algorithm Symptoms ... quadrant discomfort Signs ... PBC if 2/3 criteria ... Elevated ALP 2. ... gp210/sp100) 3.
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
spontaneous within 3- ... sensory • Before diagnosis ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #signs #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... worrisome EKG features ... #diagnosis #management
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle ... Sickle-cell disease ... The underlying pathophysiology ... precursors). 3) ... #Signs #Symptoms