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diagnosis differential management rheumatology signs algorithm als amyotrophic autoantibodies causes central cord erythematosus lateral lupus manifestations mimickers ms multiple neuromyelitis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... internal organs 3 ... skin thickening Signs ... and Symptoms: ... #symptoms #testing
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... neuritis • Partial myelitis ... impairment, Mood disorder ... Signs and symptoms ... objective evidence of neurologic
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... Comorbid autoimmune disorders ... (Systemic lupus ... Manifestations #diagnosis #neurology ... #symptoms #signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
3. ... • Bilateral signs ... and/or symptoms ... : - Multiple sclerosis ... diagnosis #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... - Transverse myelitis ... , Aspergillus 3. ... , Scleroderma, Systemic ... #diagnosis #neurology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Lung involvement 3% ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... central nervous system ... Infectious: Leprosy 3. ... Lack of UMN/LMN signs ... Differential #Diagnosis #neurology
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
fifth decades. 3. ... Vascular disorders ... weeks to months. 3. ... Multiple sclerosis ... signs or symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... (3) primary lateral ... fasciculations Common Symptoms ... more regions 3. ... #neurology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3
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