47 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... common primary disease ... Manifestations #Disease ... Systems #Diagnosis #Hematology ... #Signs #Symptoms
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... RA #diagnosis #rheumatology ... #signs #symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... internal organs 3 ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
the population Disease ... 3. ... and duration of symptoms ... angioedema Other symptoms ... Urticaria #diagnosis #rheumatology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... involvement (type 2 and 3) ... #Gauchers #Disease ... #Diagnosis #Signs ... #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... Diagnose PBC if 2/3 ... gp210/sp100) 3.
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Lung involvement 3% ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
spontaneous within 3- ... 6 months of symptom ... intervertebral disc disease ... differential #diagnosis #signs ... #symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... distribution of nearly 3: ... Signs and symptoms ... 1000 mg daily 3- ... an oral taper 3-
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
fifth decades. 3. ... Méniére's disease ... weeks to months. 3. ... Disease onset usually ... varying neurologic signs