25 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... vasculitis, Behcet ... #differential #diagnosis ... #nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
• Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... Antineutrophil #antibodies #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ): • Microscopic ... tract, and often causes ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... #nephrology #causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... urine sediment Microscopic ... → Diagnostic of ... GN or vasculitis ... #causes #urology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Vasculitis, e.g ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Microscopic polyangiitis ... Associations #diseases #diagnosis
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... Framework ANCA: ... : Microscopic Polyangiitis ... #differential #diagnosis ... #nephrology #causes
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... Churg-Strauss syndrome ... #Vessels #Diagnosis ... #Rheumatology #Diagnosis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... • ANCA Associated ... : - Microscopic ... Disease • Cogan syndrome ... #differential #diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Inflammatory causes ... spectrum disorder • ANCA-associated ... vasculitides • ... #neurology #inflammatory ... #differential #diagnosis